Journal of Science and Innovative Development ISSN 2181-4317

OBTAINING AND PROPERTIES OF THE IMPLANT FILM MADE WITH CARBOXYMETHYLCELLULOSE CONTAINING SILVER NANOPARTICLES USED FOR TREATMENT OF BURN WOUNDS

Камилов Ўткир Раимович, Фаязов Абдулазиз Джалилович, Сабурова Дилдора Шаукат қизи, Жалилов Жавлон Зафар ўғли, Юнусов Ҳайдар Эргашович, Саримсоқов Абдушкур Абдухалилович February 24, 2022 DOI: https://doi.org/10.36522/ILM-FAN/5-1-2022-4b3f2

Abstract

<p>This article studies feasibilities of making an implant-film for treatment of burn wound, based on silver nanoparticles (AgNPs) stabilized by sodiumcarboxymethylcellulose (Na-CMC) with degrees of substitution (DS) 0.65-0.90 and polymerization (DP) 200-600 synthesized using a photochemical method. The structural, physical and chemical, and physicalmechanical, burn wound healing properties as well as antimicrobial effects of implant-films containing the Na-CMC and AgNPs have been investigated. The shape, quantity, and size of the AgNPs embedded into the Na-CMC films were determined by UV-Vis spectroscopy, dynamic light scattering (DLS), atomic force microscopy (AFM) and transmission electron microscopy (TEM). It was found that the increase of silver nitrate concentration in solution of Na-CMC followed by photoirradiation leads to changes of AgNPs size and shape. It was found out that Na-CMC&nbsp;films containing AgNPs in the size ranging from 5 to 35 nm had enhanced the microbicide effects and burn wound healing properties within 14 days.</p>

Cite this article
Камилов Ўткир Раимович, Фаязов Абдулазиз Джалилович, Сабурова Дилдора Шаукат қизи, Жалилов Жавлон Зафар ўғли, Юнусов Ҳайдар Эргашович, Саримсоқов Абдушкур Абдухалилович (2022). OBTAINING AND PROPERTIES OF THE IMPLANT FILM MADE WITH CARBOXYMETHYLCELLULOSE CONTAINING SILVER NANOPARTICLES USED FOR TREATMENT OF BURN WOUNDS. Journal of Science and Innovative Development. https://doi.org/https://doi.org/10.36522/ILM-FAN/5-1-2022-4b3f2