<p>In recent years, due to increasing demand for food, there has been a need to increase crop yield, which is achieved by raising the doses of chemical fertilizers used. Their irrational use leads to serious negative consequences for the soil and the environment. Currently, diazotrophs are a potentially environmentally friendly alternative to chemical fertilizers. In this paper, processing of rice seeds of of “Avangard” variety by the association of diazotrophs A. brasilense A13-5 + A. brasilense A4-1 + A. chroococcum 14 + Azotobacter sp. 12 + Nostoc calcicola 25 + Abanaena variabilis 21 increases the growth and shaping processes of plants and increases the yield of rice by 13.2% (when the yield of rice in the control version is 72.4 C/ha). When effective diazotrophs are introduced, the potential nitrogen-fixing activity of the soil increases by 81.6%. The results obtained indicate that the use of active local strains of diazotrophs in order to develop highly effective and environmentally safe preparations is a necessary step in obtaining environmentally friendly rice products in our Republic.</p>